Labor and delivery is one of the most physiologically demanding events in a baby’s life. When something goes wrong — oxygen drops, the cord compresses, distress is missed — the consequences can last a lifetime. Many of these events are preventable when standards of care are followed.
Medically reviewed
Updated April 2026
~ min read
Continuous
Standard fetal heart rate monitoring during labor
6 hours
Window to start therapeutic hypothermia after HIE
Often preventable
With proper monitoring and timely intervention
When parents look back at the moments around their child’s birth and wonder if something went wrong, they’re asking a question that deserves a clear answer. Some cerebral palsy cases result from natural complications that no amount of medical skill could have prevented. Others result from errors that could have been avoided — missed signs of distress, delayed cesareans, mishandled deliveries. Knowing which kind of complication produced an injury matters both medically and legally.
This guide covers the perinatal complications most often linked to CP — what they are, how they cause brain injury, and what should have been done to prevent or respond to them. The goal is to give families enough understanding of the standard of care to know what questions to ask.
Some pregnancies and deliveries carry higher CP risk than others. Knowing the risk factors helps medical teams plan ahead — with extra monitoring, specialist consultations, and contingency plans — and helps families ask the right questions before, during, and after delivery.
Risk factors fall into three groups: maternal/pregnancy factors that make complications more likely, infant factors that make any complication more severe, and care factors that determine how well the team responds when something does go wrong. Most birth-related CP cases involve some combination of all three.
The impact of premature birth on cerebral palsy
Premature birth is the single biggest risk factor for CP. The reason is straightforward: premature babies have underdeveloped brains, immature lungs, and fragile blood vessels — especially in the brain. The earlier the birth, the higher the risk:
Before 28 weeks: Risk of CP is around 60–100 times higher than for term babies.
28–32 weeks: Substantially elevated risk, especially for intraventricular hemorrhage and PVL.
33–36 weeks: Lower but still elevated risk compared to term.
For a fuller breakdown of how prematurity contributes to CP and what specialized neonatal care can do, see our guide on cerebral palsy and premature birth.
How maternal infections increase risk
Infections during pregnancy — whether they cross the placenta or just trigger maternal inflammation — can raise CP risk significantly. Cytomegalovirus (CMV), rubella, toxoplasmosis, and certain bacterial infections are the most studied. The mechanism is mostly inflammatory: maternal immune activation produces signaling molecules that affect fetal brain development. For the deeper picture, see cerebral palsy and maternal infections.
Prenatal complications that affect delivery
Some events labeled “birth complications” actually have prenatal roots. A baby who has been growth-restricted for weeks may not tolerate labor well; a placenta that’s been struggling may abrupt during contractions. Watching for these signs during pregnancy is part of preventing perinatal injury.
The complications that bridge prenatal and perinatal periods often determine how the delivery itself unfolds. Identifying them ahead of time lets the team make better decisions in the moment.
Fetal distress during pregnancy
Fetal distress is a clinical pattern indicating the baby isn’t getting enough oxygen or nutrients. Signs that should trigger evaluation:
Reduced fetal movement reported by the mother
Abnormal fetal heart rate patterns on monitoring
Decelerations on a non-stress test (NST) or biophysical profile
Restricted fetal growth on ultrasound
Reduced amniotic fluid (oligohydramnios)
Persistent fetal distress can be addressed by repositioning the mother, increasing IV fluids, providing supplemental oxygen, or proceeding to delivery. Failure to recognize and respond to fetal distress is one of the most common claims in birth-injury malpractice cases.
The role of maternal health issues
Maternal conditions that raise the risk of perinatal complications:
Preeclampsia and chronic hypertension — reduce placental blood flow; can require early delivery
Diabetes (pregestational or gestational) — affects fetal growth, raises risk of shoulder dystocia and traumatic delivery
Thyroid disorders — can affect fetal neurodevelopment if untreated
Obesity — raises risk of multiple complications including operative delivery
Substance use — affects placental function and neonatal adaptation
Most of these conditions can be managed safely with appropriate prenatal care. The risk goes up sharply when they go undetected or under-treated.
What continuous monitoring is supposed to catch
Electronic fetal monitoring (EFM) tracks the baby’s heart rate alongside the mother’s contractions. Trained labor nurses watch for:
Late decelerations (signal placental insufficiency)
Variable decelerations (signal cord compression)
Loss of variability (signal compromised baby)
Tachycardia or bradycardia patterns
Perinatal events and cerebral palsy
The perinatal period — the last weeks of pregnancy through the first week of life — concentrates the most time-sensitive risks for CP. Many of these events have a narrow window for intervention, which is why prompt recognition and response matters more than almost anything else in this window.
The two perinatal categories most strongly linked to CP are oxygen deprivation events and traumatic delivery events. They produce different patterns of brain injury and call for different responses.
Labor and delivery complications
The complications that most often cause perinatal brain injury:
Prolonged labor. Especially in the second stage (pushing). Sustained pressure and stress can compromise oxygen delivery.
Abnormal fetal positioning. Breech, transverse lie, or face presentations can prolong labor or require operative delivery.
Shoulder dystocia. The baby’s head delivers but the shoulders get stuck. Can produce nerve injury (brachial plexus) or oxygen deprivation if prolonged.
Cord prolapse. The umbilical cord drops into the birth canal ahead of the baby and gets compressed. A true emergency requiring immediate cesarean.
Placental abruption. The placenta separates from the uterine wall before delivery, cutting off oxygen.
Uterine rupture. Rare but catastrophic; more common in patients with prior cesareans attempting vaginal delivery.
Misuse of forceps or vacuum extractor. Excessive force can cause skull fractures, intracranial hemorrhage, or brain swelling.
Each of these has an expected response. When the response is delayed or wrong, brain injury can result.
Understanding oxygen deprivation at birth
Birth asphyxia — severe oxygen deprivation around the time of birth — is one of the most consequential causes of CP. The clinical entity is called hypoxic-ischemic encephalopathy (HIE) when the deprivation is severe enough to produce identifiable brain dysfunction.
What HIE looks like in the immediate newborn period:
Low APGAR scores at 5 and 10 minutes
Need for resuscitation at birth
Seizures within hours of birth
Abnormal muscle tone (typically very low)
Abnormal cord blood gases (acidosis)
MRI changes in the basal ganglia, thalamus, or cortex
Therapeutic hypothermia — cooling the baby’s body temperature to about 33.5°C for 72 hours — has become standard care for moderate to severe HIE when started within 6 hours of birth. It significantly improves neurological outcomes and reduces CP severity. Failure to identify HIE in time to start cooling is a common malpractice claim. For the dedicated guide, see cerebral palsy and lack of oxygen at birth.
Common signs of preventable birth injury
If your delivery records show any of these, a malpractice review may be warranted: prolonged second-stage labor without intervention; delayed cesarean despite signs of fetal distress; APGAR scores under 7 at five minutes; resuscitation needed at birth; HIE diagnosis without prompt cooling. Our birth injury lawyers offer free record reviews. Request a free case review.
Postnatal complications that contribute to cerebral palsy
About 10–15% of CP cases are acquired after birth — from infections, head injuries, or other events in the first weeks or months of life. Many of these are preventable with prompt newborn care.
The postnatal causes of CP are sometimes overlooked because attention focuses so heavily on labor and delivery. But events in the first weeks — especially in the NICU or after early discharge — can produce serious brain injury.
Identifying neonatal infections
Newborn infections that can produce CP if not promptly treated:
Bacterial meningitis. Group B strep, E. coli, and Listeria are the most common organisms in newborns. Diagnosed by lumbar puncture; treated aggressively with IV antibiotics.
Sepsis. Bacterial bloodstream infection that can produce widespread inflammation and brain injury. Early recognition is critical.
Encephalitis. Brain inflammation, often viral. Herpes simplex virus is a particularly dangerous cause in newborns.
Severe pneumonia. Can produce hypoxia that affects the brain even when the lungs are the primary problem.
Early signs of newborn infection — temperature instability, poor feeding, lethargy, breathing difficulty, irritability — should always trigger immediate evaluation. Failure to recognize early sepsis is a recognized cause of preventable CP.
The role of birth asphyxia in postnatal injury
Birth asphyxia doesn’t always produce immediately obvious damage. Sometimes a baby seems to do well in the first hours but develops seizures, abnormal tone, or feeding difficulties days later. The brain injury that produces CP can evolve over the first 72 hours after a hypoxic event — one of the reasons careful monitoring continues well after birth in any baby with a difficult delivery.
Other postnatal causes worth knowing about:
Severe jaundice (kernicterus). Untreated high bilirubin levels can damage the basal ganglia, producing dyskinetic CP. Routine screening and phototherapy prevent it.
Stroke in infancy. Blood vessel blockage or hemorrhage can occur in the days to months after birth.
Head injury. Falls, abuse, or accidents in the first 2 years can produce CP-like injury.
Severe respiratory illness. Hypoxia from severe respiratory failure can affect the brain even in older infants.
Were you told everything was fine when it wasn’t?
Many families learn years later that their delivery records tell a different story than what they were told at the time. Our nurse advocates can help you read your records and identify any concerns worth investigating further. Get a free, confidential evaluation.
Why early diagnosis matters
Whatever caused your child’s CP, getting a confirmed diagnosis as early as possible opens the door to early-intervention services that genuinely change long-term outcomes. The brain’s plasticity is greatest in the first 3 years — when therapy can do the most good. Don’t wait for definitive answers about cause to start therapy. See our guide on how cerebral palsy is diagnosed for the full process.
Frequently asked questions about birth complications and CP
The complications most often linked to CP include oxygen deprivation (birth asphyxia or HIE), umbilical cord problems (cord prolapse, true knots, nuchal cord), placental abruption, uterine rupture, prolonged or obstructed labor, traumatic delivery (improper forceps or vacuum use), and infections during labor. Each of these can disrupt oxygen or blood flow to the baby’s brain at a critical moment.
Medical negligence contributes to CP when providers miss signs of fetal distress, delay a needed cesarean, misuse delivery instruments, or fail to manage cord or placental emergencies. Many birth-related CP cases involve breaches of the standard of care that could have been avoided. A birth injury lawyer can review delivery records to identify whether negligence played a role.
Early diagnosis of CP makes a real difference because the brain is most plastic in the first three years. Therapy started early can build motor skills, communication, and self-care abilities while the brain is still wiring up. Diagnosis also opens access to early-intervention programs, special education services, and specialized medical care.
Talk to your pediatrician any time you have specific concerns about your child’s development — missed milestones, asymmetric movement, persistent fisting, unusual muscle tone, or strong hand preference before age 2. You don’t need a diagnosis to start a workup. Trust your instinct; clinicians take parental observations seriously.
When CP results from preventable birth complications, families may be entitled to compensation through a medical malpractice claim. Settlements and verdicts in birth injury cases often reach into the millions of dollars to cover lifetime care, therapy, equipment, and lost income. Most birth injury lawyers work on contingency, meaning no upfront cost for families.
Premature birth substantially raises CP risk because preemies have underdeveloped brains and organs and face higher rates of complications — especially intraventricular hemorrhage and periventricular leukomalacia. Babies born before 32 weeks or weighing under 3.3 pounds carry the highest risk. See cerebral palsy and premature birth for the full picture.
Symptoms vary by severity but commonly include movement and coordination difficulties, abnormal muscle tone (stiff or floppy), missed motor milestones, asymmetric movement, seizures, and sometimes intellectual or learning differences. Severity ranges from very mild (a slight limp) to profound (full-time caregiving needs). For a deeper look, see our overview of cerebral palsy symptoms.